Symbol Name ID |
Pax3
paired box 3 MGI:97487 |
Darker colors indicate more annotations |
Human Phenotypes | Mandibular prognathia |
Hypoplasia of the maxilla |
Malar flattening |
Microcephaly |
Abnormality of the face |
Abnormal facial shape |
Flat face |
Narrow face |
Abnormality of the mouth |
Abnormal lip morphology |
Smooth philtrum |
Tented upper lip vermilion |
Cleft upper lip |
Cleft palate |
Narrow mouth |
Orofacial cleft |
Underdeveloped nasal alae |
Depressed nasal ridge |
Prominent nasal tip |
Depressed nasal bridge |
Narrow nasal bridge |
Prominent nasal bridge |
Wide nasal bridge |
Narrow naris |
Aplasia/Hypoplasia involving the nose |
Short nose |
Abnormal eyebrow morphology |
Synophrys |
Thick eyebrow |
White eyebrow |
White eyelashes |
Blepharophimosis |
Short palpebral fissure |
Downslanted palpebral fissures |
Epicanthus inversus |
Telecanthus |
Lacrimal duct atresia |
Disease(s) Associated with PAX3 | |||||||||||||||||||||||||||||||||||||
craniofacial-deafness-hand syndrome | |||||||||||||||||||||||||||||||||||||
Waardenburg syndrome | |||||||||||||||||||||||||||||||||||||
Waardenburg syndrome type 1 | |||||||||||||||||||||||||||||||||||||
Waardenburg syndrome type 3 |
Mouse Phenotypes | abnormal pharyngeal arch artery morphology |
abnormal sixth pharyngeal arch artery morphology |
abnormal craniofacial morphology |
abnormal craniofacial bone morphology |
abnormal bony labyrinth |
absent alisphenoid bone |
alisphenoid bone hypoplasia |
abnormal pterygoid process morphology |
absent pterygoid process |
abnormal secondary palate development |
failure of palatal shelf elevation |
abnormal palate morphology |
decreased palatal length |
cleft palate |
|
Availability | Mouse Genotype | ||||||||||||||
Pax3Sp-1H/Pax3Sp-1H | |||||||||||||||
Pax3Sp/Pax3Sp | |||||||||||||||
Gt(ROSA)26Sortm2(Pax3)Joe/Gt(ROSA)26Sortm2(Pax3)Joe Pax3tm1(cre)Joe/Pax3+ (conditional) |
|||||||||||||||
Gt(ROSA)26Sortm2(Pax3)Joe/Gt(ROSA)26Sortm2(Pax3)Joe H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
|||||||||||||||
Gt(ROSA)26Sortm2(Pax3)Joe/Gt(ROSA)26Sor+ Pax3tm1(cre)Joe/Pax3+ (conditional) |
|||||||||||||||
Gt(ROSA)26Sortm2(Pax3)Joe/Gt(ROSA)26Sor+ H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 06/12/2024 MGI 6.13 |
|
|