Symbol Name ID |
Stat5b
signal transducer and activator of transcription 5B MGI:103035 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased serum insulin-like growth factor 1 |
Decreased response to growth hormone stimulation test |
Thyroiditis |
Delayed puberty |
Disease(s) Associated with STAT5B | ||||
growth hormone insensitivity syndrome with immune dysregulation 1 | ||||
growth hormone insensitivity syndrome with immune dysregulation 2 |
Mouse Phenotypes | abnormal milk ejection |
disorganized pancreatic islets |
decreased thymocyte number |
abnormal mammary gland development |
abnormal branching of the mammary ductal tree |
abnormal mammary gland growth during lactation |
abnormal mammary gland alveolus morphology |
decreased insulin secretion |
abnormal mammary gland physiology |
hypolactation |
lactation failure |
increased mammary gland apoptosis |
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Availability | Mouse Genotype | ||||||||||||
Stat5btm1Hwd/Stat5btm1Hwd | |||||||||||||
Stat5btm1Jni/Stat5btm1Jni | |||||||||||||
Stat5btm1Mam/Stat5btm1Mam Tg(MMTV-cre)4Mam/0 (conditional) |
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Stat5btm1Mam/Stat5btm1Mam Tg(Wap-cre)11738Mam/0 (conditional) |
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Stat5btm1Mam/Stat5btm1Mam Tg(Ins2-cre)25Mgn/0 (conditional) |
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Stat5btm1Mam/Stat5btm1Mam Tg(Pdx1-cre)89.1Dam/0 (conditional) |
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Stat5btm1Mam/Stat5btm1Mam Tg(MMTV-cre)1Mam/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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