Symbol Name ID |
Cdkn1b
cyclin dependent kinase inhibitor 1B MGI:104565 |
Darker colors indicate more annotations |
Human Phenotypes | Elevated circulating growth hormone concentration |
Pituitary adenoma |
Parathyroid adenoma |
Hyperparathyroidism |
Primary hyperparathyroidism |
Hashimoto thyroiditis |
Hypothyroidism |
Carcinoid tumor |
Pancreatic endocrine tumor |
Disease(s) Associated with CDKN1B | |||||||||
multiple endocrine neoplasia type 4 |
Mouse Phenotypes | adrenal medulla hyperplasia |
enlarged adrenal glands |
increased pituitary gland weight |
enlarged pituitary gland |
pituitary gland hyperplasia |
abnormal pituitary intermediate lobe morphology |
pituitary intermediate lobe hyperplasia |
abnormal thymus morphology |
increased thymus weight |
enlarged thymus |
thymus hyperplasia |
increased thymocyte number |
abnormal prostate gland dorsolateral lobe morphology |
enlarged prostate gland |
abnormal corpus luteum morphology |
absent corpus luteum |
abnormal ovarian follicle morphology |
abnormal granulosa cell morphology |
absent tertiary ovarian follicles |
impaired ovarian folliculogenesis |
enlarged ovary |
enlarged testis |
testicular hyperplasia |
increased ovary tumor incidence |
increased pituitary gland tumor incidence |
increased pituitary adenoma incidence |
abnormal prostate gland physiology |
|
Availability | Mouse Genotype | |||||||||||||||||||||||||||
Cdkn1btm1Ako/Cdkn1btm1Ako | ||||||||||||||||||||||||||||
Cdkn1btm1Kin/Cdkn1btm1Kin | ||||||||||||||||||||||||||||
Cdkn1btm1Mlf/Cdkn1btm1Mlf | ||||||||||||||||||||||||||||
Cdkn1btm3Mlf/Cdkn1btm3Mlf | ||||||||||||||||||||||||||||
Cdkn1btm2Mlf/Cdkn1btm2Mlf Tg(Pomc1-cre)1Mlf/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 07/05/2024 MGI 6.24 |
|
|