Symbol Name ID |
Prop1
paired like homeodomain factor 1 MGI:109330 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased circulating ACTH concentration |
Decreased response to growth hormone stimulation test |
Ectopic posterior pituitary |
Anterior pituitary agenesis |
Anterior pituitary hypoplasia |
Ectopic anterior pituitary gland |
Hypopituitarism |
Abnormal prolactin level |
Pituitary hypothyroidism |
Absence of secondary sex characteristics |
Delayed puberty |
Hypogonadotropic hypogonadism |
Disease(s) Associated with PROP1 | ||||||||||||
hypopituitarism | ||||||||||||
panhypopituitarism |
Mouse Phenotypes | endocrine/exocrine gland phenotype |
abnormal pituitary gland morphology |
abnormal adenohypophysis development |
absent somatotrophs |
decreased thyrotroph cell number |
small adenohypophysis |
adenohypophysis hypoplasia |
abnormal neurohypophysis morphology |
abnormal pituitary gland development |
pituitary gland hypoplasia |
small thyroid gland |
absent corpus luteum |
abnormal ovarian follicle morphology |
abnormal granulosa cell morphology |
decreased primary ovarian follicle number |
increased primordial ovarian follicle number |
decreased secondary ovarian follicle number |
decreased tertiary ovarian follicle number |
absent tertiary ovarian follicles |
small ovary |
hypopituitarism |
|
Availability | Mouse Genotype | |||||||||||||||||||||
Prop1df/Prop1df | * | |||||||||||||||||||||
Prop1tm1Rsd/Prop1tm1Rsd | ||||||||||||||||||||||
Prop1tm1Sac/Prop1tm1Sac | ||||||||||||||||||||||
Prop1tm1Sac/Prop1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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