Symbol Name ID |
Nr5a1
nuclear receptor subfamily 5, group A, member 1 MGI:1346833 |
Darker colors indicate more annotations |
Human Phenotypes | Elevated circulating follicle stimulating hormone level |
Elevated circulating luteinizing hormone level |
Primary adrenal insufficiency |
Disease(s) Associated with NR5A1 | |||
46,XY sex reversal 3 | |||
primary ovarian insufficiency 7 | |||
Zellweger syndrome |
Mouse Phenotypes | ovary hemorrhage |
retention of the adrenal gland x-zone |
decreased granulosa cell proliferation |
abnormal adrenal gland zona glomerulosa morphology |
absent adrenal gland |
small adrenal glands |
abnormal pituitary gland morphology |
decreased gonadotroph cell number |
prostate gland hypoplasia |
seminal vesicle hypoplasia |
abnormal endometrial gland morphology |
abnormal endometrial gland development |
decreased endometrial gland number |
enlarged endometrial glands |
abnormal sex gland morphology |
absent corpus luteum |
absent mature ovarian follicles |
abnormal ovarian follicle number |
decreased primary ovarian follicle number |
decreased primordial ovarian follicle number |
decreased secondary ovarian follicle number |
decreased tertiary ovarian follicle number |
impaired ovarian folliculogenesis |
ovarian follicular cyst |
decreased ovary weight |
small ovary |
ovary hypoplasia |
absent ovary |
abnormal testis morphology |
abnormal seminiferous tubule morphology |
seminiferous tubule degeneration |
abnormal testis development |
abnormal testis cord formation |
abnormal Leydig cell morphology |
decreased Leydig cell number |
increased Leydig cell number |
decreased testis weight |
small testis |
testis hypoplasia |
absent testes |
cryptorchism |
agonadal |
abnormal ovary physiology |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||
Nr5a1em1Kemi/Nr5a1em1Kemi | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm1.1Hain/Nr5a1tm1.1Hain | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm1Enl/Nr5a1tm1Enl | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm1Jmi/Nr5a1tm1Jmi | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm1Klp/Nr5a1tm1Klp | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm2.1Klp/Nr5a1tm2.1Klp | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm3Klp/Nr5a1tm3Klp | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1em1Kemi/Nr5a1+ | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm1.1Hain/Nr5a1+ | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm1Klp/Nr5a1tm2Klp | ||||||||||||||||||||||||||||||||||||||||||||
Nr5a1tm2Klp/Nr5a1tm2Klp Tg(Cga-cre)3Sac/0 (conditional) |
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Cyp11b2tm1.1(cre)Brlt/Cyp11b2+ Nr5a1tm2Klp/Nr5a1tm2Klp (conditional) |
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Amhr2tm3(cre)Bhr/Amhr2+ Nr5a1tm1Klp/Nr5a1tm2Klp (conditional) |
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Gt(ROSA)26Sortm2(CAG-Nr5a1)Fjd/Gt(ROSA)26Sor+ Pgrtm2(cre)Lyd/Pgr+ (conditional) |
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Nr5a1tm2Klp/Nr5a1tm2.1Klp Tg(Cga-cre)3Sac/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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