Symbol
Name
ID

Fas
Fas cell surface death receptor
MGI:95484

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Type I diabetes mellitus	Elevated sweat chloride	Exocrine pancreatic insufficiency	Pancreatitis	Thyroid adenoma	Thyroid carcinoma	Thyroiditis
Disease(s) Associated with FAS	Type I diabetes mellitus	Elevated sweat chloride	Exocrine pancreatic insufficiency	Pancreatitis	Thyroid adenoma	Thyroid carcinoma	Thyroiditis
autoimmune lymphoproliferative syndrome
cystic fibrosis
pre-eclampsia

Mouse Phenotypes

abnormal submandibular gland morphology

submandibular gland inflammation

salivary gland inflammation

endocrine/exocrine gland phenotype

abnormal gland morphology

thymus cortex atrophy

abnormal thymus medulla morphology

increased thymus weight

enlarged thymus

thymus atrophy

abnormal thyroid gland morphology

abnormal thyroid follicle morphology

lacrimal gland atrophy

abnormal thymus involution

thyroid gland inflammation

lacrimal gland inflammation

Availability

Mouse Genotype

Fas^lpr/Fas^lpr

Fas^tm1Dlo/Fas^tm1Dlo

Fas^tm1Cgn/Fas^tm1Cgn
Tg(Cd4-cre)1Cwi/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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