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Symbol
Name
ID
Ptgs2
prostaglandin-endoperoxide synthase 2
MGI:97798
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Diabetes mellitus
Elevated sweat chloride
Exocrine pancreatic insufficiency
Pancreatitis
Pancreatic adenocarcinoma
Abnormality of the adrenal glands
Hyperthyroidism
Hypothyroidism
Diabetes insipidus
Disease(s) Associated with PTGS2
cystic fibrosis
pancreatic cancer
sarcoidosis

Mouse Phenotypes
impaired granulosa cell differentiation
sebaceous gland hyperplasia
pancreas necrosis
abnormal corpus luteum morphology
absent corpus luteum
abnormal cumulus expansion
small ovary
increased sebaceous gland adenoma incidence
decreased susceptibility to induced pancreatitis
Availability Mouse Genotype
Ptgs2tm1Jed/Ptgs2tm1Jed
Ptgs2tm1Unc/Ptgs2tm1Unc
Tg(K5-Ptgs2)675Kmd/Tg(K5-Ptgs2)675Kmd
Tg(K5-Ptgs2)19Kmd/0
Tg(K5-Ptgs2)667Kmd/0
Tg(K5-Ptgs2)675Kmd/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/05/2024
MGI 6.24
The Jackson Laboratory