Symbol Name ID |
Lep
leptin MGI:104663 |
Darker colors indicate more annotations |
Human Phenotypes | Increased waist to hip ratio |
Obesity |
Disease(s) Associated with LEP | ||
congenital leptin deficiency | ||
type 2 diabetes mellitus |
Mouse Phenotypes | increased body fat mass |
heart left ventricle hypertrophy |
increased heart weight |
increased pancreas weight |
decreased lean body mass |
increased lean body mass |
decreased body weight |
increased body weight |
obese |
decreased body length |
increased body length |
abnormal body weight |
increased susceptibility to diet-induced obesity |
abnormal postnatal growth |
increased growth rate |
enlarged kidney |
increased kidney weight |
increased liver weight |
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Availability | Mouse Genotype | ||||||||||||||||||
Lepm1Btlr/Lepm1Btlr | |||||||||||||||||||
Lepm1Yst/Lepm1Yst | |||||||||||||||||||
Lepm2Btlr/Lepm2Btlr | |||||||||||||||||||
Lepob/Lepob | |||||||||||||||||||
Lepob/Lepob Tg(Npy-MAPT/Sapphire)1Rck/0 |
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Lepob/Lepob Tg(Pomc-MAPT/Topaz)1Rck/0 |
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Leptm1.2Gvcao/Leptm1.2Gvcao | |||||||||||||||||||
Leptm1Kry/Leptm1Kry | |||||||||||||||||||
Lepob/Lep+ | |||||||||||||||||||
Lepob/Lepob-2J | |||||||||||||||||||
Tg(Apcs-Lep)1Yog/0 | |||||||||||||||||||
Leptm1.1Gvcao/Leptm1.1Gvcao Tg(Adipoq-cre)1Evdr/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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