Symbol Name ID |
Npc1
NPC intracellular cholesterol transporter 1 MGI:1097712 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Fetal ascites |
Splenomegaly |
Hepatomegaly |
Disease(s) Associated with NPC1 | |||
Niemann-Pick disease type C1 |
Mouse Phenotypes | abnormal olfactory epithelium morphology |
abnormal olfactory sensory neuron morphology |
growth/size/body region phenotype |
decreased body weight |
slow postnatal weight gain |
weight loss |
decreased body size |
increased lung weight |
enlarged liver |
increased liver weight |
enlarged spleen |
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Availability | Mouse Genotype | |||||||||||
Npc1m1N/Npc1m1N | ||||||||||||
Npc1nmf164/Npc1nmf164 | ||||||||||||
Npc1spm/Npc1spm | ||||||||||||
Npc1tm1.1Dso/Npc1tm1.1Dso | ||||||||||||
Npc1tm1.2Apl/Npc1tm1.2Apl | ||||||||||||
Npc1tm1Mbjg/Npc1tm1Mbjg | ||||||||||||
Npc1tm1Tacf/Npc1tm1Tacf | ||||||||||||
Npc1m1N/Npc1tm1.2Apl | ||||||||||||
Npc1tm1Tacf/Npc1tm2Tacf | ||||||||||||
Npc1m1N/Npc1tm1.1Apl Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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Npc1m1N/Npc1tm1.1Apl Tg(Syn1-cre)671Jxm/0 (conditional) |
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Npc1tm1.1Apl/Npc1tm1.2Apl Tg(Pcp2-cre)2Mpin/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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