Symbol Name ID |
Mecp2
methyl CpG binding protein 2 MGI:99918 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Short neck |
Short stature |
Decreased body weight |
Failure to thrive |
Cachexia |
Obesity |
Growth delay |
Disease(s) Associated with MECP2 | |||||||
Rett syndrome | |||||||
severe congenital encephalopathy due to MECP2 mutation | |||||||
syndromic X-linked intellectual disability Lubs type | |||||||
X-linked intellectual disability-psychosis-macroorchidism syndrome |
Mouse Phenotypes | increased heart weight |
abnormal tooth morphology |
malocclusion |
growth/size/body region phenotype |
decreased body weight |
slow postnatal weight gain |
weight loss |
cachexia |
increased body weight |
obese |
abnormal body weight |
increased susceptibility to age related obesity |
postnatal growth retardation |
increased liver weight |
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Availability | Mouse Genotype | ||||||||||||||
Mecp2tm1.1Bird/Mecp2tm1.1Bird | |||||||||||||||
Mecp2tm1.1Vnar/Mecp2tm1.1Vnar | * | ||||||||||||||
Mecp2tm1.1Dhy/Mecp2+ | * | ||||||||||||||
Mecp2tm1.1Irsf/Mecp2+ | |||||||||||||||
Mecp2tm1.1Jae/Mecp2+ | |||||||||||||||
Mecp2tm1.1Joez/Mecp2+ | |||||||||||||||
Mecp2tm1.1Jtc/Mecp2+ | |||||||||||||||
Mecp2tm1Nlnd/Mecp2+ | |||||||||||||||
Mecp2tm2Bird/Mecp2+ | |||||||||||||||
Mecp2tm1.1Bird/Y | ! | ! | |||||||||||||
Mecp2tm1.1Dhy/Y | * | ||||||||||||||
Mecp2tm1.1Irsf/Y | |||||||||||||||
Mecp2tm1.1Jae/Y | |||||||||||||||
Mecp2tm1.1Joez/Y | |||||||||||||||
Mecp2tm1.1Jtc/Y | |||||||||||||||
Mecp2tm1Bird/Y | *! | ! | |||||||||||||
Mecp2tm1Jae/Y | |||||||||||||||
Mecp2tm1Nlnd/Y | |||||||||||||||
Mecp2tm1Pplt/Y | |||||||||||||||
Mecp2tm1Vnar/Y | * | ||||||||||||||
Mecp2tm2.1Jae/Y | |||||||||||||||
Mecp2tm2.1Joez/Y | * | ||||||||||||||
Mecp2tm3.1Bird/Y | |||||||||||||||
Mecp2tm4.1Bird/Y | |||||||||||||||
Mecp2tm5.1Bird/Y | |||||||||||||||
Mecp2tm6.1Bird/Y | |||||||||||||||
Mecp2tm1Pplt/0 | |||||||||||||||
Mecp2tm1Jae/Mecp2+ Tg(Nes-cre)1Atp/0 (conditional) |
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Mecp2tm2Bird/Mecp2+ Tg(CAG-cre/Esr1*)5Amc/? (conditional) |
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Mecp2tm1Bird/Y Tg(Nes-cre)1Kln/0 (conditional) |
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Mecp2tm1Bird/Y Tg(Slc32a1-cre)2.1Hzo/0 (conditional) |
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Mecp2tm1Jae/Y Tg(Nes-cre)1Atp/0 (conditional) |
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Mecp2tm1Jae/Y Tg(Camk2a-cre)93Kln/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/27/2024 MGI 6.24 |
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