Symbol Name ID |
S1pr2
sphingosine-1-phosphate receptor 2 MGI:99569 |
Darker colors indicate more annotations |
Human Phenotypes | Sensorineural hearing impairment |
Disease(s) Associated with S1PR2 | |
autosomal recessive nonsyndromic deafness 68 |
Mouse Phenotypes | abnormal stria vascularis vasculature morphology |
otosclerosis |
detached Reissner membrane |
abnormal Rosenthal canal morphology |
cochlear outer hair cell degeneration |
cochlear hair cell degeneration |
abnormal organ of Corti morphology |
organ of Corti degeneration |
abnormal stria vascularis morphology |
abnormal strial basal cell morphology |
abnormal strial intermediate cell morphology |
abnormal strial marginal cell morphology |
stria vascularis degeneration |
thin stria vascularis |
abnormal tectorial membrane morphology |
small scala media |
vestibular saccular degeneration |
abnormal vestibular labyrinth morphology |
decreased otolith number |
enlarged otoliths |
decreased endocochlear potential |
increased or absent threshold for auditory brainstem response |
absent distortion product otoacoustic emissions |
impaired hearing |
deafness |
abnormal vestibular system physiology |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||
S1pr2stdf/S1pr2stdf | |||||||||||||||||||||||||||
S1pr2tm1Ajml/S1pr2tm1Ajml | |||||||||||||||||||||||||||
S1pr2tm1Rlp/S1pr2tm1Rlp |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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