Symbol Name ID |
Lep
leptin MGI:104663 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased T cell activation |
Decreased proportion of CD4-positive helper T cells |
Disease(s) Associated with LEP | ||
congenital leptin deficiency |
Mouse Phenotypes | abnormal osteoclast differentiation |
decreased T cell proliferation |
decreased NK cell number |
decreased CD4-positive, alpha-beta T cell number |
increased macrophage cell number |
decreased spleen weight |
decreased splenocyte number |
abnormal microglial cell physiology |
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Availability | Mouse Genotype | ||||||||
Lepm1Yst/Lepm1Yst | |||||||||
Lepob/Lepob | |||||||||
Leptm1b(EUCOMM)Hmgu/Leptm1b(EUCOMM)Hmgu |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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