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Symbol
Name
ID

Pdcd1
programmed cell death 1
MGI:104879

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Hemolytic anemia	Leukopenia	Thrombocytopenia
Disease(s) Associated with PDCD1
systemic lupus erythematosus

Mouse Phenotypes

increased B cell proliferation

enlarged spleen

abnormal leukopoiesis

abnormal myelopoiesis

decreased B-1 B cell number

increased B-1 B cell number

increased B cell number

increased T-helper 1 cell number

decreased CD8-positive, alpha-beta T cell number

decreased regulatory T cell number

increased regulatory T cell number

increased lymphocyte cell number

abnormal immunoglobulin level

increased IgA level

increased IgG2b level

increased IgG3 level

increased IgM level

abnormal T cell activation

Availability

Mouse Genotype

Pdcd1^tm1.1Liux/Pdcd1^tm1.1Liux

Pdcd1^tm1.1Shr/Pdcd1^tm1.1Shr

Pdcd1^tm1Hon/Pdcd1^tm1Hon

Pdcd1^tm1Llc/Pdcd1^tm1Llc

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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