Symbol Name ID |
Il4ra
interleukin 4 receptor, alpha MGI:105367 |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA concentration |
Increased circulating IgG concentration |
Decreased circulating antibody concentration |
Paraproteinemia |
Anemia |
Multiple myeloma |
Elevated erythrocyte sedimentation rate |
Splenomegaly |
Disease(s) Associated with IL4R | ||||||||
multiple myeloma | ||||||||
rheumatoid arthritis |
Mouse Phenotypes | impaired macrophage chemotaxis |
decreased T cell proliferation |
increased eosinophil cell number |
decreased T-helper 2 cell number |
increased monocyte cell number |
abnormal T-helper 2 cell morphology |
abnormal microglial cell morphology |
decreased IgE level |
increased IgE level |
decreased IgG1 level |
increased IgG2a level |
increased IgG level |
abnormal T-helper 2 physiology |
abnormal macrophage physiology |
abnormal macrophage activation involved in immune response |
|
Availability | Mouse Genotype | |||||||||||||||
Il4raM1Btlr/Il4raM1Btlr | ||||||||||||||||
Il4raM2Btlr/Il4raM2Btlr | ||||||||||||||||
Il4ratm1Fbb/Il4ratm1Fbb | ||||||||||||||||
Il4ratm1Sz/Il4ratm1Sz | ||||||||||||||||
Il4ratm1Tch/Il4ratm1Tch | ||||||||||||||||
Il4ratm2Tch/Il4ratm2Tch | ||||||||||||||||
Il4ratm3.1Tch/Il4ratm3.1Tch | ||||||||||||||||
Il4ratm1Fbb/Il4ratm2Fbb Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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