Symbol Name ID |
Crebbp
CREB binding protein MGI:1098280 |
Darker colors indicate more annotations |
Human Phenotypes | Leukemia |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Lymphoma |
Accessory spleen |
Polysplenia |
Disease(s) Associated with CREBBP | |||||||
acute lymphoblastic leukemia | |||||||
acute myeloid leukemia | |||||||
Rubinstein-Taybi syndrome |
Mouse Phenotypes | small thymus |
decreased thymocyte number |
enlarged spleen |
abnormal definitive hematopoiesis |
abnormal common myeloid progenitor cell morphology |
decreased common myeloid progenitor cell number |
decreased double-positive T cell number |
increased double-positive T cell number |
extramedullary hematopoiesis |
anemia |
impaired hematopoiesis |
increased bone marrow cell number |
abnormal megakaryocyte morphology |
increased megakaryocyte cell number |
abnormal granulocyte morphology |
increased granulocyte number |
decreased B cell number |
absent pre-B cells |
decreased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
decreased T cell number |
decreased lymphocyte cell number |
decreased hematopoietic stem cell number |
abnormal leukocyte morphology |
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Availability | Mouse Genotype | ||||||||||||||||||||||||
CrebbpGt(U-San)112Imeg/CrebbpGt(U-San)112Imeg | |||||||||||||||||||||||||
Crebbptm1Pkb/Crebbptm1Pkb | |||||||||||||||||||||||||
Crebbptm1Sis/Crebbptm1Sis | |||||||||||||||||||||||||
Crebbptm1Dli/Crebbp+ | |||||||||||||||||||||||||
Crebbptm1Jvd/Crebbptm1Jvd Tg(MMTV-cre)4Mam/0 (conditional) |
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Crebbptm1Jvd/Crebbptm1Jvd Tg(Lck-cre)548Jxm/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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