Symbol Name ID |
Diaph1
diaphanous related formin 1 MGI:1194490 |
Darker colors indicate more annotations |
Human Phenotypes | Menorrhagia |
Post-partum hemorrhage |
Impaired platelet aggregation |
Thrombocytopenia |
Macrothrombocytopenia |
Disease(s) Associated with DIAPH1 | |||||
autosomal dominant nonsyndromic deafness 1 |
Mouse Phenotypes | abnormal leukocyte migration |
decreased T cell proliferation |
increased spleen weight |
abnormal definitive hematopoiesis |
extramedullary hematopoiesis |
anemia |
abnormal bone marrow cell morphology/development |
increased bone marrow cell number |
echinocytosis |
increased neutrophil cell number |
increased granulocyte number |
decreased B-1 B cell number |
abnormal CD4-positive, alpha-beta T cell number |
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number |
increased central memory CD4-positive, alpha-beta T cell number |
increased effector memory CD4-positive, alpha-beta T cell number |
decreased CD4-positive, alpha-beta T cell number |
abnormal CD8-positive, alpha-beta T cell number |
increased central memory CD8 positive, alpha-beta T cell number |
decreased effector memory CD8-positive, alpha-beta T cell number |
increased effector memory CD8-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta memory T cell number |
increased CD8-positive, alpha-beta memory T cell number |
decreased CD8-positive, naive alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased T cell number |
increased single-positive T cell number |
decreased lymphocyte cell number |
increased monocyte cell number |
increased leukocyte cell number |
abnormal spleen morphology |
abnormal spleen germinal center morphology |
absent spleen white pulp |
decreased IgE level |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
Diaph1M1Btlr/Diaph1M1Btlr | ||||||||||||||||||||||||||||||||||||
Diaph1M2Btlr/Diaph1M2Btlr | ||||||||||||||||||||||||||||||||||||
Diaph1m3Btlr/Diaph1m3Btlr | ||||||||||||||||||||||||||||||||||||
Diaph1tm1.1Sna/Diaph1tm1.1Sna | ||||||||||||||||||||||||||||||||||||
Diaph1tm1Asal/Diaph1tm1Asal | ||||||||||||||||||||||||||||||||||||
Diaph1M1Btlr/Diaph1+ | ||||||||||||||||||||||||||||||||||||
Diaph1M2Btlr/Diaph1+ | ||||||||||||||||||||||||||||||||||||
Diaph1tm1Asal/Diaph1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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