Symbol Name ID |
Rab27a
RAB27A, member RAS oncogene family MGI:1861441 |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Reduced delayed hypersensitivity |
Petechiae |
Pancytopenia |
Neutropenia |
Hemophagocytosis |
Splenomegaly |
Hepatosplenomegaly |
Disease(s) Associated with RAB27A | |||||||
Griscelli syndrome type 2 |
Mouse Phenotypes | decreased platelet ATP level |
abnormal NK cell degranulation |
decreased NK cell degranulation |
decreased erythrocyte cell number |
decreased neutrophil cell number |
thrombocytopenia |
abnormal platelet dense granule morphology |
decreased platelet ADP level |
decreased platelet dense granule number |
decreased platelet serotonin level |
decreased leukocyte cell number |
pancytopenia |
abnormal neutrophil physiology |
impaired natural killer cell mediated cytotoxicity |
abnormal cytotoxic T cell physiology |
decreased cytotoxic T cell cytolysis |
decreased platelet aggregation |
abnormal platelet dense granule physiology |
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Availability | Mouse Genotype | ||||||||||||||||||
Rab27aash/Rab27aash | ! | ! | ! | ! | |||||||||||||||
Rab27acct/Rab27acct |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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