Symbol Name ID |
Il21
interleukin 21 MGI:1890474 |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgE level |
Decreased circulating IgG level |
Hemolytic anemia |
Decreased proportion of class-switched memory B cells |
Abnormal T cell count |
Leukopenia |
Thrombocytopenia |
Disease(s) Associated with IL21 | |||||||
common variable immunodeficiency 11 | |||||||
systemic lupus erythematosus |
Mouse Phenotypes | abnormal class switch recombination |
abnormal T cell differentiation |
decreased germinal center B cell number |
decreased CD4-positive, alpha-beta T cell number |
abnormal CD4-positive, alpha beta T cell morphology |
abnormal gamma-delta T cell morphology |
abnormal spleen germinal center morphology |
decreased spleen germinal center number |
abnormal germinal center B cell physiology |
increased IgE level |
decreased IgG1 level |
abnormal CD4-positive, alpha-beta T cell physiology |
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Availability | Mouse Genotype | ||||||||||||
Il21tm1Lex/Il21tm1Lex | |||||||||||||
Il21tm1Llit/Il21tm1Llit |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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