Symbol
Name
ID

Cd274
CD274 antigen
MGI:1926446

Phenotype annotations related to hematopoietic system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

hematopoietic system phenotype

decreased T cell apoptosis

increased T cell proliferation

abnormal T-helper 1 cell differentiation

decreased germinal center B cell number

decreased plasma cell number

decreased T helper 1 cell number

decreased T-helper 17 cell number

decreased CD8-positive, alpha-beta T cell number

increased CD8-positive, alpha-beta T cell number

increased T cell number

increased activated T cell number

abnormal T cell morphology

abnormal CD4-positive, alpha beta T cell morphology

abnormal CD8-positive, alpha beta T cell morphology

decreased IgG1 level

increased IgG1 level

decreased IgG2a level

increased IgG2c level

abnormal T follicular helper cell physiology

abnormal CD8-positive, alpha-beta T cell physiology

abnormal regulatory T cell physiology

Availability

Mouse Genotype

Cd274^tm1.1Lex/Cd274^tm1.1Lex

Cd274^tm1Lpc/Cd274^tm1Lpc

Cd274^tm1Shr/Cd274^tm1Shr

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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