Symbol Name ID |
Asxl1
ASXL transcriptional regulator 1 MGI:2684063 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal thymus morphology |
hepatosplenomegaly |
enlarged spleen |
spleen hyperplasia |
abnormal blood cell morphology/development |
abnormal definitive hematopoiesis |
abnormal common myeloid progenitor cell morphology |
abnormal lymphopoiesis |
increased double-negative T cell number |
abnormal myelopoiesis |
myeloid hyperplasia |
extramedullary hematopoiesis |
anemia |
impaired hematopoiesis |
abnormal bone marrow cell morphology/development |
decreased bone marrow cell number |
increased bone marrow cell number |
increased granulocyte monocyte progenitor cell number |
abnormal megakaryocyte morphology |
increased megakaryocyte cell number |
decreased erythroid progenitor cell number |
increased erythroid progenitor cell number |
decreased erythrocyte cell number |
decreased hemoglobin content |
decreased mean corpuscular hemoglobin |
increased mean corpuscular hemoglobin concentration |
increased nucleated erythrocyte cell number |
increased number of Howell-Jolly bodies |
polychromatophilia |
decreased neutrophil cell number |
increased neutrophil cell number |
abnormal neutrophil morphology |
thrombocytopenia |
thrombocytosis |
decreased mature B cell number |
decreased B cell number |
decreased pre-B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased T cell number |
increased single-positive T cell number |
decreased lymphocyte cell number |
decreased monocyte cell number |
increased monocyte cell number |
decreased leukocyte cell number |
increased leukocyte cell number |
increased myeloid cell number |
decreased hematopoietic stem cell number |
increased hematopoietic stem cell number |
abnormal hematopoietic stem cell morphology |
decreased megakaryocyte-erythroid progenitor cell number |
abnormal leukocyte morphology |
abnormal myeloid cell morphology |
abnormal spleen morphology |
decreased spleen red pulp amount |
decreased spleen weight |
small spleen |
spleen atrophy |
abnormal spleen white pulp morphology |
decreased splenocyte number |
abnormal neutrophil physiology |
abnormal hematopoietic stem cell physiology |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Asxl1tm1.1Mjxu/Asxl1tm1.1Mjxu | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Asxl1tm1Bc/Asxl1tm1Bc | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Asxl1tm1.1Mjxu/Asxl1+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Asxl1tm1a(EUCOMM)Wtsi/Asxl1+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Tg(Vav1-Asxl1*Y588X)#Fcy/0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Asxl1tm1.1Iaai/Asxl1tm1.1Iaai Tg(Mx1-cre)1Cgn/0 (conditional) |
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Asxl1tm1.1Iaai/Asxl1tm1.1Iaai Tg(VAV1-cre)1Graf/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/02/2024 MGI 6.13 |
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