Symbol Name ID |
Ank1
ankyrin 1, erythroid MGI:88024 |
Darker colors indicate more annotations |
Human Phenotypes | Increased mean corpuscular hemoglobin concentration |
Reticulocytosis |
Anemia |
Hemolytic anemia |
Spontaneous hemolytic crises |
Spherocytosis |
Increased red cell osmotic fragility |
Hypofibrinogenemia |
Hypercoagulability |
Extramedullary hematopoiesis |
Splenomegaly |
Disease(s) Associated with ANK1 | |||||||||||
hereditary spherocytosis | |||||||||||
hereditary spherocytosis type 1 |
Mouse Phenotypes | abnormal thymus development |
enlarged spleen |
increased spleen weight |
abnormal common myeloid progenitor cell morphology |
decreased common myeloid progenitor cell number |
abnormal erythropoiesis |
abnormal myelopoiesis |
extramedullary hematopoiesis |
anemia |
hemolytic anemia |
hypochromic anemia |
microcytic anemia |
increased erythroid progenitor cell number |
erythroblastosis |
abnormal erythrocyte morphology |
decreased erythrocyte cell number |
low mean erythrocyte cell number |
increased erythrocyte cell number |
polycythemia |
decreased hematocrit |
decreased cellular hemoglobin content |
increased hemoglobin concentration distribution width |
decreased hemoglobin content |
decreased mean corpuscular hemoglobin |
decreased mean corpuscular hemoglobin concentration |
decreased mean corpuscular volume |
increased nucleated erythrocyte cell number |
anisocytosis |
acanthocytosis |
anisopoikilocytosis |
hyperchromasia |
increased erythrocyte protoporphyrin level |
microcytosis |
poikilocytosis |
schistocytosis |
polychromatophilia |
spherocytosis |
stomatocytosis |
increased neutrophil cell number |
thrombocytosis |
abnormal leukocyte cell number |
increased lymphocyte cell number |
increased leukocyte cell number |
reticulocytosis |
abnormal spleen morphology |
decreased spleen iron level |
increased spleen iron level |
abnormal erythrocyte physiology |
increased erythrocyte clearance |
hemolysis |
increased erythrocyte osmotic fragility |
|
Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1ity16/Ank1ity16 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1M1Btlr/Ank1M1Btlr | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1M1Wlst/Ank1M1Wlst | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1MRI23420/Ank1MRI23420 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1nb/Ank1nb | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1Rbc2/Ank1Rbc2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1ity16/Ank1+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1M1Btlr/Ank1+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1M1Wlst/Ank1+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1MRI23420/Ank1+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1nb/Ank1+ | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Ank1Rbc2/Ank1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 08/02/2024 MGI 6.24 |
|
|