About Help FAQ

Symbol
Name
ID

Cd27
CD27 antigen
MGI:88326

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Decreased lymphocyte proliferation in response to mitogen	Decreased circulating antibody level	Pancytopenia	Aplastic anemia	Hemophagocytosis	Lymphoma	Hodgkin lymphoma	Lymphoproliferative disorder	Splenomegaly	Hepatosplenomegaly
Disease(s) Associated with CD27
lymphoproliferative syndrome 2

Mouse Phenotypes		increased T cell apoptosis	abnormal leukopoiesis	decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	decreased regulatory T cell number	increased leukocyte cell number	abnormal spleen morphology	abnormal T cell physiology	abnormal CD4-positive, alpha-beta T cell physiology	abnormal cytotoxic T cell physiology
Availability	Mouse Genotype	increased T cell apoptosis	abnormal leukopoiesis		decreased regulatory T cell number	increased leukocyte cell number	abnormal spleen morphology	abnormal T cell physiology	abnormal CD4-positive, alpha-beta T cell physiology	abnormal cytotoxic T cell physiology
	Cd27^{em1(IMPC)Ccpcz}/Cd27^{em1(IMPC)Ccpcz}
	Cd27^tm1Jbo/Cd27^tm1Jbo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24