Symbol Name ID |
Fech
ferrochelatase MGI:95513 |
Darker colors indicate more annotations |
Human Phenotypes | Reduced erythrocyte uroporphyrinogen III cosynthase activity |
Hemolytic anemia |
Iron deficiency anemia |
Microcytic anemia |
Thrombocytopenia |
Splenomegaly |
Disease(s) Associated with FECH | ||||||
cutaneous porphyria | ||||||
erythropoietic protoporphyria |
Mouse Phenotypes | increased spleen weight |
abnormal erythropoiesis |
hypochromic anemia |
abnormal erythrocyte morphology |
decreased erythrocyte cell number |
decreased hematocrit |
decreased hemoglobin content |
increased red blood cell distribution width |
anisocytosis |
increased erythrocyte protoporphyrin level |
leptocytosis |
polychromatophilia |
reticulocytosis |
decreased erythrocyte osmotic fragility |
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Availability | Mouse Genotype | ||||||||||||||
Fechm1Pas/Fechm1Pas |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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