Symbol Name ID |
Nos3
nitric oxide synthase 3, endothelial cell MGI:97362 |
Darker colors indicate more annotations |
Human Phenotypes | Persistence of hemoglobin F |
Increased mean corpuscular volume |
Reticulocytosis |
Hemolytic anemia |
Chronic hemolytic anemia |
Hypochromic anemia |
Iron deficiency anemia |
Microcytic anemia |
Leukocytosis |
Acute lymphoblastic leukemia |
T-cell acute lymphoblastic leukemias |
Acute myeloid leukemia |
Superficial thrombophlebitis |
Thrombocytosis |
Lymphoma |
Abnormality of the spleen |
Splenic infarction |
Hepatosplenomegaly |
Disease(s) Associated with NOS3 | ||||||||||||||||||
acute lymphoblastic leukemia | ||||||||||||||||||
acute myeloid leukemia | ||||||||||||||||||
Behcet's disease | ||||||||||||||||||
cystic fibrosis | ||||||||||||||||||
sickle cell anemia |
Mouse Phenotypes | enhanced leukocyte tethering or rolling |
abnormal leukocyte adhesion |
enlarged spleen |
increased basophil cell number |
increased eosinophil cell number |
increased neutrophil cell number |
decreased lymphocyte cell number |
abnormal spleen morphology |
abnormal neutrophil physiology |
abnormal osteoclast physiology |
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Availability | Mouse Genotype | ||||||||||
Nos3em1(IMPC)Mbp/Nos3em1(IMPC)Mbp | |||||||||||
Nos3tm1Plh/Nos3tm1Plh | |||||||||||
Nos3tm1Unc/Nos3tm1Unc |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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