Symbol Name ID |
Pbx1
pre B cell leukemia homeobox 1 MGI:97495 |
Darker colors indicate more annotations |
Mouse Phenotypes | abnormal thymus morphology |
small thymus |
thymus hypoplasia |
ectopic thymus |
abnormal definitive hematopoiesis |
decreased common myeloid progenitor cell number |
absent common myeloid progenitor cells |
decreased pro-B cell number |
decreased double-negative T cell number |
anemia |
impaired hematopoiesis |
decreased bone marrow cell number |
abnormal common lymphocyte progenitor cell morphology |
low mean erythrocyte cell number |
decreased hematocrit |
decreased mature B cell number |
decreased B cell number |
decreased pre-B cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
decreased T cell number |
decreased hematopoietic stem cell number |
abnormal hematopoietic stem cell morphology |
abnormal spleen morphology |
abnormal spleen mesenchyme morphology |
small spleen |
spleen hypoplasia |
absent spleen |
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Availability | Mouse Genotype | ||||||||||||||||||||||||||||
Pbx1em1Dunw/Pbx1em1Dunw | |||||||||||||||||||||||||||||
Pbx1tm1Mlc/Pbx1tm1Mlc | |||||||||||||||||||||||||||||
Pbx1tm1Mlc/Pbx1tm2.1Mlc | |||||||||||||||||||||||||||||
Nkx2-5tm2(cre)Rph/Nkx2-5+ Pbx1tm1.1Koss/Pbx1tm1.1Koss (conditional) |
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Pbx1tm1.1Koss/Pbx1tm1.1Koss Tg(WT1-cre)AG11Dbdr/0 (conditional) |
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Pbx1tm1Koss/Pbx1tm1Koss Nkx2-5tm2(cre)Rph/Nkx2-5+ (conditional) |
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Pbx1tm1.1Koss/Pbx1tm1.2Koss Tmem163Tg(ACTB-cre)2Mrt/0 (conditional) |
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Pbx1tm1Mlc/Pbx1tm3.1Mlc Tg(Tek-cre)1Ywa/0 (conditional) |
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Pbx1tm1Mlc/Pbx1tm3.1Mlc Tg(Mx1-cre)1Cgn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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