Symbol Name ID |
Prf1
perforin 1 (pore forming protein) MGI:97551 |
Darker colors indicate more annotations |
Mouse Phenotypes | decreased T cell apoptosis |
decreased NK cell degranulation |
decreased bone marrow cell number |
decreased erythrocyte cell number |
decreased mean corpuscular hemoglobin concentration |
decreased neutrophil cell number |
thrombocytopenia |
increased activated T cell number |
decreased leukocyte cell number |
pancytopenia |
increased spleen red pulp amount |
abnormal spleen white pulp morphology |
abnormal leukocyte physiology |
abnormal lymphocyte physiology |
abnormal NK cell physiology |
impaired natural killer cell mediated cytotoxicity |
abnormal cytotoxic T cell physiology |
decreased cytotoxic T cell cytolysis |
abnormal T cell activation |
abnormal macrophage activation involved in immune response |
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Availability | Mouse Genotype | ||||||||||||||||||||
Prf1tm1.1(KOMP)Vlcg/Prf1tm1.1(KOMP)Vlcg | |||||||||||||||||||||
Prf1tm1Clrk/Prf1tm1Clrk | |||||||||||||||||||||
Prf1tm1Sdz/Prf1tm1Sdz | |||||||||||||||||||||
Prf1tm1Tsc/Prf1tm1Tsc | |||||||||||||||||||||
Prf1tm1Sdz/Prf1+ | |||||||||||||||||||||
Prf1tm1Tsc/Prf1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/02/2024 MGI 6.13 |
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