Symbol Name ID |
Prkcd
protein kinase C, delta MGI:97598 |
Darker colors indicate more annotations |
Human Phenotypes | Reduced natural killer cell activity |
Absent isohemagglutinin level |
Increased circulating antibody concentration |
Autoimmune hemolytic anemia |
Decreased proportion of class-switched memory B cells |
Decreased proportion of memory B cells |
Increased proportion autoreactive unresponsive CD21-/low B cells |
Increased B cell count |
Autoimmune thrombocytopenia |
Lymphoproliferative disorder |
Elevated erythrocyte sedimentation rate |
Splenomegaly |
Hepatosplenomegaly |
Disease(s) Associated with PRKCD | |||||||||||||
autoimmune lymphoproliferative syndrome type 3 |
Mouse Phenotypes | increased B cell apoptosis |
increased B cell proliferation |
enlarged spleen |
increased transitional stage B cell number |
abnormal plasma cell differentiation |
increased erythrocyte cell number |
decreased neutrophil cell number |
increased follicular B cell number |
increased marginal zone B cell number |
increased B cell number |
increased NK cell number |
increased spleen germinal center number |
abnormal neutrophil physiology |
abnormal immunoglobulin level |
increased IgA level |
increased IgG1 level |
increased IgM level |
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Availability | Mouse Genotype | |||||||||||||||||
Prkcdm2Btlr/Prkcdm2Btlr | ||||||||||||||||||
Prkcdtm1.1Chou/Prkcdtm1.1Chou | ||||||||||||||||||
Prkcdtm1Kin/Prkcdtm1Kin | ||||||||||||||||||
Prkcdtm1Msg/Prkcdtm1Msg | ||||||||||||||||||
Prkcdtm1Qxu/Prkcdtm1Qxu |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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