Symbol Name ID |
Srsf2
serine and arginine-rich splicing factor 2 MGI:98284 |
Darker colors indicate more annotations |
Human Phenotypes | Acute myeloid leukemia |
Myelodysplasia |
Disease(s) Associated with SRSF2 | ||
acute myeloid leukemia | ||
myelodysplastic syndrome |
Mouse Phenotypes | absent thymus corticomedullary boundary |
decreased thymus weight |
small thymus |
decreased thymocyte number |
abnormal erythropoiesis |
abnormal T cell differentiation |
increased double-negative T cell number |
decreased double-positive T cell number |
abnormal myelopoiesis |
failure of myelopoiesis |
macrocytic anemia |
impaired hematopoiesis |
abnormal erythroid progenitor cell morphology |
abnormal neutrophil morphology |
decreased B cell number |
decreased T cell number |
increased hematopoietic stem cell number |
abnormal spleen white pulp morphology |
abnormal hematopoietic system physiology |
abnormal hematopoietic stem cell physiology |
bone marrow failure |
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Availability | Mouse Genotype | |||||||||||||||||||||
Srsf2tm1Xdfu/Srsf2tm1Xdfu Tg(Lck-cre)I57Jxm/? (conditional) |
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Srsf2tm1Xdfu/Srsf2tm1Xdfu Tg(Mx1-cre)1Cgn/? (conditional) |
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Srsf2tm1.1Oaw/Srsf2+ Tg(Mx1-cre)1Cgn/? (conditional) |
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Srsf2tm1Xdfu/Srsf2+ Tg(Lck-cre)I57Jxm/? (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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