Symbol Name ID |
Pdx1
pancreatic and duodenal homeobox 1 MGI:102851 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Reduced C-peptide level |
Neonatal insulin-dependent diabetes mellitus |
Maturity-onset diabetes of the young |
Type II diabetes mellitus |
Insulin resistance |
Disease(s) Associated with PDX1 | |||||
maturity-onset diabetes of the young type 4 | |||||
pancreatic agenesis | |||||
type 2 diabetes mellitus |
Mouse Phenotypes | homeostasis/metabolism phenotype |
increased glucagon secretion |
decreased insulin secretion |
increased circulating glucose level |
hyperglycemia |
decreased circulating insulin level |
dehydration |
impaired glucose tolerance |
increased urine glucose level |
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Availability | Mouse Genotype | |||||||||
Pdx1tm1.1Stof/Pdx1tm1.1Stof | ||||||||||
Pdx1tm1Cvw/Pdx1tm1Cvw | ||||||||||
Pdx1tm1Ted/Pdx1tm1Ted | ||||||||||
Pdx1tm2Cvw/Pdx1tm2Cvw | ||||||||||
Pdx1tm1.1Stof/Pdx1+ | ||||||||||
Pdx1tm1b(EUCOMM)Wtsi/Pdx1+ | ||||||||||
Pdx1tm1Cvw/Pdx1+ | ||||||||||
Pdx1tm1Cvw/Pdx1tm1.1Stof | ||||||||||
Pdx1tm1Macd/Pdx1+ | ||||||||||
Pdx1tm1Ted/Pdx1+ | ||||||||||
Pdx1tm2Cvw/Pdx1+ | * | |||||||||
Pdx1tm2Cvw/Pdx1tm3Cvw | ||||||||||
Pdx1tm3Cvw/Pdx1+ | ||||||||||
Pdx1tm1Heed/Pdx1tm1Heed Tg(Ins2-cre)1Heed/0 (conditional) |
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Pdx1tm1Cvw/Pdx1tm4Cvw Tg(Ins2-cre)25Mgn/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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