Symbol Name ID |
Il18
interleukin 18 MGI:107936 |
Darker colors indicate more annotations |
Human Phenotypes | Abnormality of metabolism/homeostasis |
Hyperbilirubinemia |
Conjugated hyperbilirubinemia |
Increased total bilirubin |
Unconjugated hyperbilirubinemia |
Elevated circulating C-reactive protein concentration |
Increased alpha-globulin |
Elevated circulating osteopontin level |
Elevated circulating hepatic transaminase concentration |
Elevated gamma-glutamyltransferase level |
Elevated circulating alkaline phosphatase concentration |
Elevated erythrocyte sedimentation rate |
Fever |
Food intolerance |
Acholic stools |
Dark yellow urine |
Hematuria |
Decreased level of D-mannose in urine |
Disease(s) Associated with IL18 | ||||||||||||||||||
atopic dermatitis | ||||||||||||||||||
Behcet's disease | ||||||||||||||||||
biliary atresia | ||||||||||||||||||
temporal arteritis |
Mouse Phenotypes | increased circulating histamine level |
decreased circulating interferon-gamma level |
decreased circulating interleukin-18 level |
increased circulating interleukin-18 level |
decreased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
decreased energy expenditure |
abnormal nitric oxide homeostasis |
decreased oxygen consumption |
impaired glucose tolerance |
abnormal cytokine level |
abnormal interferon level |
abnormal interleukin level |
abnormal tumor necrosis factor level |
decreased cerebral infarct size |
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Availability | Mouse Genotype | |||||||||||||||
Il18tm1Aki/Il18tm1Aki | ||||||||||||||||
Il18tm1Khe/Il18tm1Khe | ||||||||||||||||
Il18tm1Liew/Il18tm1Liew | ||||||||||||||||
Tg(KRT14-Il18)#Knak/0 | ||||||||||||||||
Tg(SFTPC-Il18)AThos/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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