Symbol Name ID |
Kl
klotho MGI:1101771 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Disease(s) Associated with KL | |||||||
coronary artery disease |
Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased insulin secretion |
decreased circulating glucose level |
hypoglycemia |
decreased circulating insulin level |
increased circulating noradrenaline level |
decreased circulating parathyroid hormone level |
increased circulating parathyroid hormone level |
abnormal circulating mineral level |
increased circulating calcium level |
increased circulating phosphate level |
abnormal circulating protein level |
decreased circulating serum albumin level |
decreased body temperature |
dehydration |
abnormal glucose homeostasis |
improved glucose tolerance |
increased insulin sensitivity |
increased urine calcium level |
calcinosis |
abnormal vitamin D level |
increased vitamin D level |
increased alkaline phosphatase activity |
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Availability | Mouse Genotype | |||||||||||||||||||||||
Klecalc1/Klecalc1 | ||||||||||||||||||||||||
Klecalc2/Klecalc2 | ||||||||||||||||||||||||
Klkl/Klkl | ||||||||||||||||||||||||
Klm1Anu/Klm1Anu | ||||||||||||||||||||||||
Kltm1.2Tel/Kltm1.2Tel | ||||||||||||||||||||||||
Kltm1Lex/Kltm1Lex | ||||||||||||||||||||||||
Kltm1Yin/Kltm1Yin | ||||||||||||||||||||||||
Klkl/Kl+ | ||||||||||||||||||||||||
Kltm1.1Tel/Kltm1.1Tel Tg(Cdh16-cre)91Igr/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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