|
Symbol Name ID |
Ncoa3
nuclear receptor coactivator 3 MGI:1276535 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased resting energy expenditure |
| Disease(s) Associated with NCOA3 | |
| obesity |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
impaired exercise endurance |
decreased susceptibility to diet-induced obesity |
impaired adaptive thermogenesis |
increased circulating bilirubin level |
decreased circulating glucose level |
hyperglycemia |
decreased circulating estradiol level |
decreased circulating glucagon level |
decreased circulating insulin level |
decreased circulating insulin-like growth factor I level |
increased circulating insulin-like growth factor I level |
increased circulating leptin level |
decreased circulating HDL cholesterol level |
decreased circulating cholesterol level |
decreased circulating free fatty acids level |
decreased circulating triglyceride level |
increased circulating interleukin-1 beta level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
decreased body temperature |
increased energy expenditure |
decreased carbon dioxide production |
increased carbon dioxide production |
decreased oxygen consumption |
increased oxygen consumption |
increased respiratory quotient |
abnormal glucose homeostasis |
impaired glucose tolerance |
improved glucose tolerance |
increased liver glycogen level |
increased insulin sensitivity |
insulin resistance |
abnormal hormone level |
decreased adiponectin level |
increased liver triglyceride level |
abnormal exercise endurance |
increased incidence of tumors by chemical induction |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
| Ncoa3tm1.1Bwo/Ncoa3tm1.1Bwo | * | ||||||||||||||||||||||||||||||||||||||
| Ncoa3tm1Jxu/Ncoa3tm1Jxu | |||||||||||||||||||||||||||||||||||||||
| Ncoa3tm1Rsd/Ncoa3tm1Rsd | |||||||||||||||||||||||||||||||||||||||
| Ncoa3tm2.2Jxu/Ncoa3tm2.2Jxu | |||||||||||||||||||||||||||||||||||||||
| Ncoa3tm1b(EUCOMM)Wtsi/Ncoa3+ | |||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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