Symbol Name ID |
Lrp6
low density lipoprotein receptor-related protein 6 MGI:1298218 |
Darker colors indicate more annotations |
Human Phenotypes | Heat intolerance |
Disease(s) Associated with LRP6 | |
tooth agenesis |
Mouse Phenotypes | decreased susceptibility to diet-induced obesity |
decreased susceptibility to induced hypothermia |
increased circulating bilirubin level |
decreased circulating glucose level |
increased circulating LDL cholesterol level |
increased circulating triglyceride level |
increased circulating VLDL triglyceride level |
hyperlipidemia |
increased circulating aspartate transaminase level |
improved glucose tolerance |
increased insulin sensitivity |
insulin resistance |
increased circulating adiponectin level |
abnormal lipid homeostasis |
increased liver cholesterol level |
increased cholesterol level |
abnormal fatty acids level |
decreased liver triglyceride level |
increased liver triglyceride level |
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Availability | Mouse Genotype | |||||||||||||||||||
Lrp6tm1Arma/Lrp6tm1Arma | ||||||||||||||||||||
Lrp6Gt(LST067)Byg/Lrp6+ | ||||||||||||||||||||
Lrp6tm1Arma/Lrp6+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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