Symbol Name ID |
Slc40a1
solute carrier family 40 (iron-regulated transporter), member 1 MGI:1315204 |
* | Aspects of the system are reported to show a normal phenotype. |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Elevated transferrin saturation |
Increased circulating ferritin concentration |
Glucose intolerance |
Diabetes mellitus |
Impaired glucose tolerance |
Hepatic steatosis |
Disease(s) Associated with SLC40A1 | ||||||
hemochromatosis type 4 |
Mouse Phenotypes | homeostasis/metabolism phenotype |
increased heart iron level |
decreased intestinal iron level |
increased intestinal iron level |
increased pancreas iron level |
decreased spleen iron level |
increased spleen iron level |
increased circulating triglyceride level |
decreased circulating iron level |
increased circulating iron level |
increased circulating lipase level |
increased circulating ferritin level |
decreased circulating unsaturated transferrin level |
increased circulating unsaturated transferrin level |
abnormal enzyme/coenzyme level |
edema |
abnormal iron homeostasis |
increased brain iron level |
increased kidney iron level |
abnormal liver iron level |
decreased liver iron level |
increased liver iron level |
hemochromatosis |
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Availability | Mouse Genotype | |||||||||||||||||||||||
Slc40a1ffe/Slc40a1ffe | *! | ! | ||||||||||||||||||||||
Slc40a1Pcm/Slc40a1Pcm | ||||||||||||||||||||||||
Slc40a1tm1.1Mmfe/Slc40a1tm1.1Mmfe | ||||||||||||||||||||||||
Slc40a1ffe/Slc40a1+ | ||||||||||||||||||||||||
Slc40a1Pcm/Slc40a1+ | ||||||||||||||||||||||||
Slc40a1tm1.1Mmfe/Slc40a1+ | ||||||||||||||||||||||||
Slc40a1tm1b(EUCOMM)Hmgu/Slc40a1+ | ||||||||||||||||||||||||
Slc40a1tm1Nca/Slc40a1+ | ||||||||||||||||||||||||
Meox2tm1(cre)Sor/Meox2+ Slc40a1tm2Nca/Slc40a1tm2Nca (conditional) |
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Slc40a1tm2Nca/Slc40a1tm2Nca Tg(Vil1-cre/ERT2)23Syr/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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