Symbol Name ID |
Foxa2
forkhead box A2 MGI:1347476 |
Darker colors indicate more annotations |
Human Phenotypes | Type II diabetes mellitus |
Insulin resistance |
Disease(s) Associated with FOXA2 | ||
type 2 diabetes mellitus |
Mouse Phenotypes | abnormal insulin secretion |
decreased circulating glucose level |
hypoglycemia |
decreased circulating glucagon level |
decreased circulating insulin level |
increased circulating insulin level |
decreased circulating free fatty acids level |
increased circulating free fatty acids level |
increased circulating triglyceride level |
cyanosis |
increased carbon dioxide production |
increased oxygen consumption |
abnormal glucose homeostasis |
improved glucose tolerance |
increased glycogen level |
increased insulin sensitivity |
increased liver triglyceride level |
abnormal metabolism |
increased basal metabolism |
increased susceptibility to injury |
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Availability | Mouse Genotype | ||||||||||||||||||||
Foxa2tm1.1Khk/Foxa2+ | |||||||||||||||||||||
Foxa2tm1Dnl/Foxa2+ | |||||||||||||||||||||
Foxa2tm1.1Stf/Foxa2tm1.1Stf Tg(Nes-cre)1Kln/0 (conditional) |
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Foxa2tm1.1Stf/Foxa2tm1.1Stf (conditional) | |||||||||||||||||||||
Foxa2tm1Khk/Foxa2tm1Khk (conditional) | |||||||||||||||||||||
Foxa2tm1Khk/Foxa2tm1Khk Tg(SFTPC-rtTA)5Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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Foxa2tm1Khk/Foxa2tm1Khk Tg(Foxa3-cre)1Khk/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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