Symbol Name ID |
Crls1
cardiolipin synthase 1 MGI:1913836 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased activity of mitochondrial complex I |
Decreased activity of mitochondrial complex III |
Decreased activity of mitochondrial complex IV |
Nonimmune hydrops fetalis |
Unexplained fevers |
Disease(s) Associated with CRLS1 | |||||
combined oxidative phosphorylation deficiency 57 |
Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased susceptibility to diet-induced obesity |
impaired adaptive thermogenesis |
increased fasting circulating glucose level |
decreased oxygen consumption |
decreased respiratory quotient |
insulin resistance |
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Availability | Mouse Genotype | |||||||
Crls1tm1Geno/Crls1tm1Geno Gt(ROSA)26Sortm1(cre/ERT2)Tyj/Gt(ROSA)26Sor+ (conditional) |
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Crls1tm1Geno/Crls1tm1Geno Tg(Adipoq-cre)1Evdr/0 (conditional) |
* | |||||||
Crls1tm1Geno/Crls1tm1Geno Tg(Ucp1-cre/ERT2)426Biat/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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