Symbol Name ID |
Mtor
mechanistic target of rapamycin kinase MGI:1928394 |
Darker colors indicate more annotations |
Human Phenotypes | Elevated circulating creatinine concentration |
Type II diabetes mellitus |
Insulin resistance |
Abnormal urinary electrolyte concentration |
Hematuria |
Albuminuria |
Disease(s) Associated with MTOR | ||||||
autosomal dominant polycystic kidney disease | ||||||
type 2 diabetes mellitus |
Mouse Phenotypes | increased response of heart to induced stress |
abnormal autophagy |
abnormal translation |
decreased blood urea nitrogen level |
decreased circulating glucose level |
decreased circulating insulin-like growth factor I level |
decreased circulating LDL cholesterol level |
increased circulating LDL cholesterol level |
ascites |
pleural effusion |
abnormal oxygen consumption |
decreased oxygen consumption |
increased skeletal muscle glycogen level |
abnormal urine homeostasis |
|
Availability | Mouse Genotype | ||||||||||||||
Mtortm1.1Clyn/Mtor+ | |||||||||||||||
Mtortm1a(EUCOMM)Wtsi/Mtor+ | |||||||||||||||
Mtortm1.1Gcon/Mtortm1.1Gcon A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
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Mtortm1.2Koz/Mtortm1.2Koz Tg(ACTA1-cre)79Jme/? (conditional) |
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Mtortm1.1Seq/Mtortm1.2Seq Tg(Nphs2-cre)1Seq/? (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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