Symbol Name ID |
Cd40lg
CD40 ligand MGI:88337 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Hypercalcemia |
Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating creatinine concentration |
Hyperproteinemia |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Pleural effusion |
Abnormality of vitamin B12 metabolism |
Amyloidosis |
Increased circulating free T3 |
Increased circulating free T4 concentration |
Decreased thyroid-stimulating hormone level |
Disease(s) Associated with CD40LG | ||||||||||||||||||||
coronary artery disease | ||||||||||||||||||||
Graves' disease | ||||||||||||||||||||
multiple myeloma |
Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased platelet aggregation |
abnormal blood coagulation |
abnormal thrombosis |
increased bleeding time |
increased urine protein level |
decreased cerebral infarct size |
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Availability | Mouse Genotype | |||||||
Cd40lgtm1Imx/Cd40lgtm1Imx | ||||||||
Cd40lgtm1Imx/Y | ||||||||
Tg(Igh-V-CD40lg)#Tsub/0 | ||||||||
Cd40lgtm1Imx/? | ||||||||
Cd40lgtm1Parl/Cd40lgtm1Parl Tg(Cd4-cre)1Cwi/0 (conditional) |
* | |||||||
Cd40lgtm1Parl/Cd40lgtm1Parl Commd10Tg(Vav1-icre)A2Kio/Commd10+ (conditional) |
* | |||||||
Cd40lgtm1Parl/Cd40lgtm1Parl Tg(Tek-cre)1Ywa/0 (conditional) |
* | |||||||
Cd40lgtm1Parl/Y Commd10Tg(Vav1-icre)A2Kio/Commd10+ (conditional) |
* | |||||||
Cd40lgtm1Parl/Y Tg(Cd4-cre)1Cwi/0 (conditional) |
* | |||||||
Cd40lgtm1Parl/Y Tg(Tek-cre)1Ywa/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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