|
Symbol Name ID |
Htr2c
5-hydroxytryptamine (serotonin) receptor 2C MGI:96281 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased resting energy expenditure |
| Disease(s) Associated with HTR2C | |
| obesity |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
increased susceptibility to diet-induced obesity |
decreased circulating glucose level |
increased circulating glucose level |
hyperglycemia |
increased circulating ghrelin level |
increased circulating glucagon level |
increased circulating corticosterone level |
decreased circulating insulin level |
increased circulating insulin level |
decreased circulating insulin-like growth factor I level |
decreased circulating leptin level |
increased circulating leptin level |
increased circulating growth hormone level |
decreased circulating cholesterol level |
decreased circulating triglyceride level |
abnormal body temperature |
increased energy expenditure |
dehydration |
decreased oxygen consumption |
increased oxygen consumption |
abnormal respiratory quotient |
impaired glucose tolerance |
insulin resistance |
abnormal tumor necrosis factor level |
abnormal metabolism |
increased basal metabolism |
abnormal response/metabolism to endogenous compounds |
increased susceptibility to xenobiotic induced morbidity/mortality |
increased physiological sensitivity to xenobiotic |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||
| Htr2ctm2Knk/Htr2ctm2Knk | * | ||||||||||||||||||||||||||||||
| Htr2ctm1.1Eme/Y | |||||||||||||||||||||||||||||||
| Htr2ctm1Arte/Y | * | ||||||||||||||||||||||||||||||
| Htr2ctm1Jke/Y | |||||||||||||||||||||||||||||||
| Htr2ctm1Jul/Y | |||||||||||||||||||||||||||||||
| Htr2ctm1Knk/Y | * | ||||||||||||||||||||||||||||||
| Htr2ctm2Knk/Y | * | ||||||||||||||||||||||||||||||
| Htr2ctm2Jke/Htr2ctm2Jke Tg(Pomc1-cre)16Lowl/0 (conditional) |
* | ||||||||||||||||||||||||||||||
| Htr2ctm2Jke/Htr2ctm2Jke Tg(Pomc-cre/ERT2)#Jke/0 (conditional) |
* | ||||||||||||||||||||||||||||||
| Htr2ctm1Jke/Y Tg(Pomc1-cre)16Lowl/0 (conditional) |
* | ||||||||||||||||||||||||||||||
| Htr2ctm2Jke/Y Tg(Zp3-cre)93Knw/0 (conditional) |
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| Htr2ctm2Jke/Y Tg(Pomc1-cre)16Lowl/0 (conditional) |
* | ||||||||||||||||||||||||||||||
| Htr2ctm2Jke/Y Tg(Pomc-cre/ERT2)#Jke/0 (conditional) |
* | ||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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