Symbol Name ID |
Il1rn
interleukin 1 receptor antagonist MGI:96547 |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Abnormality of metabolism/homeostasis |
Hypercalcemia |
Decreased level of 1,5 anhydroglucitol in serum |
Hyperbilirubinemia |
Elevated circulating creatinine concentration |
Elevated circulating C-reactive protein concentration |
Hyperproteinemia |
Elevated circulating hepatic transaminase concentration |
Elevated circulating alkaline phosphatase concentration |
Elevated erythrocyte sedimentation rate |
Hyperglycemia |
Diabetes mellitus |
Type II diabetes mellitus |
Insulin resistance |
Ketoacidosis |
Joint swelling |
Pleural effusion |
Fever |
Recurrent fever |
Abnormality of vitamin B12 metabolism |
Hematuria |
Pyuria |
Increased level of L-fucose in urine |
Proteinuria |
Hyperoxaluria |
Amyloidosis |
Renal amyloidosis |
Disease(s) Associated with IL1RN | |||||||||||||||||||||||||||||||
calcium oxalate nephrolithiasis | |||||||||||||||||||||||||||||||
graft-versus-host disease | |||||||||||||||||||||||||||||||
IgA glomerulonephritis | |||||||||||||||||||||||||||||||
Muckle-Wells syndrome | |||||||||||||||||||||||||||||||
multiple myeloma | |||||||||||||||||||||||||||||||
rheumatoid arthritis | |||||||||||||||||||||||||||||||
Sjogren's syndrome | |||||||||||||||||||||||||||||||
stomach cancer | |||||||||||||||||||||||||||||||
systemic lupus erythematosus | |||||||||||||||||||||||||||||||
type 1 diabetes mellitus | |||||||||||||||||||||||||||||||
type 2 diabetes mellitus |
Mouse Phenotypes | abnormal vascular wound healing |
decreased circulating cholesterol level |
decreased circulating interleukin-1 level |
increased circulating interleukin-1 level |
decreased circulating interleukin-6 level |
increased circulating interleukin-6 level |
decreased circulating serum amyloid protein level |
increased circulating serum amyloid protein level |
abnormal body temperature homeostasis |
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Availability | Mouse Genotype | |||||||||
Il1rntm1Dih/Il1rntm1Dih | ||||||||||
Il1rntm1Yiw/Il1rntm1Yiw | ||||||||||
Tg(Il1rn)1Dih/Tg(Il1rn)1Dih | ||||||||||
Tg(Il1rn)1Dih/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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