Symbol Name ID |
Ins2
insulin II MGI:96573 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Decreased level of 1,5 anhydroglucitol in serum |
Reduced C-peptide level |
Elevated circulating hepatic transaminase concentration |
Hyperglycemia |
Diabetes mellitus |
Diabetic ketoacidosis |
Maturity-onset diabetes of the young |
Type I diabetes mellitus |
Type II diabetes mellitus |
Insulin resistance |
Ketoacidosis |
Disease(s) Associated with INS | |||||||||||
maturity-onset diabetes of the young type 10 | |||||||||||
pancreatic cancer | |||||||||||
permanent neonatal diabetes mellitus | |||||||||||
type 1 diabetes mellitus | |||||||||||
type 1 diabetes mellitus 2 | |||||||||||
type 2 diabetes mellitus |
Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased insulin secretion |
increased insulin secretion |
abnormal homeostasis |
increased circulating glucose level |
hyperglycemia |
decreased circulating insulin level |
decreased circulating leptin level |
decreased circulating triglyceride level |
increased energy expenditure |
increased carbon dioxide production |
increased oxygen consumption |
decreased respiratory quotient |
abnormal glucose homeostasis |
impaired glucose tolerance |
increased urine glucose level |
increased insulin sensitivity |
insulin resistance |
decreased liver triglyceride level |
decreased skeletal muscle triglyceride level |
albuminuria |
|
Availability | Mouse Genotype | |||||||||||||||||||||
Ins2Akita/Ins2Akita | ||||||||||||||||||||||
Ins2C95S/Ins2C95S | ||||||||||||||||||||||
Ins2tm1(cre/ERT2)Kcmm/Ins2tm1(cre/ERT2)Kcmm | * | |||||||||||||||||||||
Ins2tm1Jja/Ins2tm1Jja | ||||||||||||||||||||||
Ins2tm1Rll/Ins2tm1Rll | * | |||||||||||||||||||||
Ins1tm1.1(cre)Thor/Ins1+ | * | |||||||||||||||||||||
Ins2Akita/Ins2+ | * | |||||||||||||||||||||
Ins2C95S/Ins2+ | ||||||||||||||||||||||
Ins2em#Arak/Ins2+ | ||||||||||||||||||||||
Ins2Akita/? |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 09/17/2024 MGI 6.24 |
|
|