Symbol Name ID |
Nos3
nitric oxide synthase 3, endothelial cell MGI:97362 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Unconjugated hyperbilirubinemia |
Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating creatinine concentration |
Elevated circulating hepatic transaminase concentration |
Increased circulating lactate dehydrogenase concentration |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Elevated sweat chloride |
Dehydration |
Hypercalciuria |
Decreased level of D-mannose in urine |
Disease(s) Associated with NOS3 | |||||||||||||||
Behcet's disease | |||||||||||||||
coronary artery disease | |||||||||||||||
cystic fibrosis | |||||||||||||||
sickle cell anemia |
Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal vascular wound healing |
increased susceptibility to neuronal excitotoxicity |
abnormal blood homeostasis |
increased blood urea nitrogen level |
abnormal circulating glucose level |
decreased fasting circulating glucose level |
decreased circulating glucose level |
increased circulating glucose level |
increased circulating estradiol level |
decreased circulating insulin level |
increased circulating insulin level |
increased circulating leptin level |
increased circulating osteocalcin level |
increased circulating progesterone level |
increased circulating LDL cholesterol level |
increased circulating cholesterol level |
increased circulating free fatty acids level |
increased circulating triglyceride level |
hyperlipidemia |
decreased circulating phosphate level |
abnormal circulating protein level |
increased circulating creatine kinase level |
increased circulating renin level |
abnormal glomerular capillary thrombosis |
cyanosis |
decreased body temperature |
abnormal dopamine level |
pulmonary alveolar edema |
abnormal glucose homeostasis |
improved glucose tolerance |
insulin resistance |
decreased adiponectin level |
abnormal serotonin level |
decreased prostaglandin level |
albuminuria |
abnormal response/metabolism to endogenous compounds |
decreased physiological sensitivity to xenobiotic |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
Nos3em1(IMPC)Mbp/Nos3em1(IMPC)Mbp | |||||||||||||||||||||||||||||||||||||||
Nos3tm1.2Taka/Nos3tm1.2Taka | |||||||||||||||||||||||||||||||||||||||
Nos3tm1Gdk/Nos3tm1Gdk | |||||||||||||||||||||||||||||||||||||||
Nos3tm1Plh/Nos3tm1Plh | * | ||||||||||||||||||||||||||||||||||||||
Nos3tm1Unc/Nos3tm1Unc | * | ||||||||||||||||||||||||||||||||||||||
Nos3tm2.1Plh/Nos3tm2.1Plh | |||||||||||||||||||||||||||||||||||||||
Nos3tm3.1Plh/Nos3tm3.1Plh |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 07/05/2024 MGI 6.24 |
|
|