Symbol Name ID |
Thrb
thyroid hormone receptor beta MGI:98743 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Increased circulating thyroglobulin concentration |
Diabetes mellitus |
Type II diabetes mellitus |
Increased circulating free T3 |
Increased circulating free T4 concentration |
Increased circulating T4 concentration |
Elevated circulating thyroid-stimulating hormone concentration |
Epiphyseal stippling |
Disease(s) Associated with THRB | ||||||||
selective pituitary thyroid hormone resistance | ||||||||
thyroid hormone resistance syndrome |
Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal circulating hormone level |
decreased circulating insulin-like growth factor I level |
decreased circulating thyroid-stimulating hormone level |
increased circulating thyroid-stimulating hormone level |
decreased circulating thyroxine level |
increased circulating thyroxine level |
increased circulating triiodothyronine level |
increased circulating levels of thyroid hormone |
decreased circulating glycerol level |
abnormal pituitary hormone level |
increased thyroid-stimulating hormone level |
abnormal thyroid hormone level |
increased thyroxine level |
increased triiodothyronine level |
abnormal response/metabolism to endogenous compounds |
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Availability | Mouse Genotype | ||||||||||||||||
Thrbtm1.1Syc/Thrbtm1.1Syc | |||||||||||||||||
Thrbtm1Df/Thrbtm1Df | |||||||||||||||||
Thrbtm1Ehs/Thrbtm1Ehs | * | ||||||||||||||||
Thrbtm1Few/Thrbtm1Few | |||||||||||||||||
Thrbtm1Olc/Thrbtm1Olc | |||||||||||||||||
Thrbtm2a(EUCOMM)Wtsi/Thrbtm2a(EUCOMM)Wtsi | |||||||||||||||||
Thrbtm2Df/Thrbtm2Df | |||||||||||||||||
Thrbtm2Few/Thrbtm2Few | |||||||||||||||||
Thrbtm3.1Df/Thrbtm3.1Df | |||||||||||||||||
Thrbtm3Few/Thrbtm3Few | |||||||||||||||||
Thrbtm4Few/Thrbtm4Few | |||||||||||||||||
Thrbtm6.1Few/Thrbtm6.1Few | * | ||||||||||||||||
Thrbtm1.1Syc/Thrb+ | |||||||||||||||||
Thrbtm2Few/Thrb+ | |||||||||||||||||
Thrbtm6.1Few/Thrb+ | * | ||||||||||||||||
Thrbtm1Mkni/Thrbtm1Mkni Hprt1tm1(TG-cre)1Sasr/Y (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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