Symbol Name ID |
Fasl
Fas ligand MGI:99255 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Abnormal lymphocyte apoptosis |
Decreased lymphocyte apoptosis |
Increased circulating IgA concentration |
Increased circulating IgE concentration |
Decreased circulating IgG concentration |
Increased circulating IgG concentration |
Decreased circulating total IgM |
Increased circulating IgM level |
Decreased specific anti-polysaccharide antibody level |
Increased circulating antibody concentration |
Reduced delayed hypersensitivity |
Elevated circulating creatinine concentration |
Elevated circulating hepatic transaminase concentration |
Reduced leukocyte alkaline phosphatase |
Diabetes mellitus |
Type I diabetes mellitus |
Type II diabetes mellitus |
Insulin resistance |
Edema |
Hydrops fetalis |
Pulmonary edema |
Fever |
Abnormal circulating vitamin B12 concentration |
Proteinuria |
Disease(s) Associated with FASLG | ||||||||||||||||||||||||
autoimmune lymphoproliferative syndrome | ||||||||||||||||||||||||
chronic myeloid leukemia | ||||||||||||||||||||||||
pancreatic cancer | ||||||||||||||||||||||||
pre-eclampsia | ||||||||||||||||||||||||
type 2 diabetes mellitus |
Mouse Phenotypes | homeostasis/metabolism phenotype |
increased circulating tumor necrosis factor level |
decreased circulating alanine transaminase level |
skin edema |
abnormal interleukin level |
increased urine protein level |
decreased susceptibility to injury |
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Availability | Mouse Genotype | |||||||
Faslgld/Faslgld | * | |||||||
Fasltm1.1Ast/Fasltm1.1Ast | ||||||||
Fasltm1.1Lest/Fasltm1.1Lest |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/03/2024 MGI 6.24 |
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