Symbol Name ID |
Nr3c2
nuclear receptor subfamily 3, group C, member 2 MGI:99459 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Hyperkalemia |
Hyponatremia |
Metabolic acidosis |
Dehydration |
Disease(s) Associated with NR3C2 | ||||
autosomal dominant pseudohypoaldosteronism type 1 |
Mouse Phenotypes | homeostasis/metabolism phenotype |
increased circulating angiotensin II level |
increased circulating aldosterone level |
increased circulating potassium level |
decreased circulating sodium level |
increased circulating renin level |
dehydration |
abnormal ion homeostasis |
abnormal renal sodium reabsorption |
increased urine sodium level |
increased renin activity |
|
Availability | Mouse Genotype | |||||||||||
Nr3c2tm1Gsc/Nr3c2tm1Gsc | ||||||||||||
Nr3c2tm1Gsc/Nr3c2+ | ||||||||||||
Nr3c2tm2Gsc/Nr3c2tm2Gsc Tg(Aqp2-cre/ERT2)4Gsc/0 (conditional) |
* |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 06/12/2024 MGI 6.13 |
|
|