Symbol
Name
ID

Mecp2
methyl CpG binding protein 2
MGI:99918

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Increased serum serotonin
Disease(s) Associated with MECP2	Increased serum serotonin
autistic disorder

Mouse Phenotypes

homeostasis/metabolism phenotype

increased response of heart to induced stress

increased circulating LDL cholesterol level

increased circulating cholesterol level

increased circulating triglyceride level

abnormal body temperature

decreased body temperature

decreased noradrenaline level

decreased serotonin level

increased brain cholesterol level

increased liver triglyceride level

Availability

Mouse Genotype

Mecp2^tm1.1Bird/Mecp2⁺

Mecp2^tm1.1Bird/Y

Mecp2^tm1.1Jae/Y

Mecp2^tm2Bird/Y

Mecp2^tm1Jae/Y
Chat^tm2(cre)Lowl/Chat⁺ (conditional)

Chat^tm2(cre)Lowl/Chat⁺
Mecp2^tm2Bird/Y (conditional)

Mecp2^tm1Jae/Y
Tg(Myh6-cre)2182Mds/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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