Symbol Name ID |
Cd86
CD86 antigen MGI:101773 |
! | Indicates phenotype varies with strain background. |
Darker colors indicate more annotations |
Human Phenotypes | Chronic lymphatic leukemia |
Autoimmunity |
Platelet antibody positive |
Cellular immunodeficiency |
Asthma |
Disease(s) Associated with CD86 | |||||
asthma | |||||
autoimmune thrombocytopenic purpura | |||||
chronic lymphocytic leukemia | |||||
type 1 diabetes mellitus |
Mouse Phenotypes | abnormal T cell proliferation |
decreased T cell proliferation |
spleen hyperplasia |
abnormal B cell differentiation |
decreased B cell number |
decreased CD4-positive, alpha-beta T cell number |
increased CD4-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
decreased regulatory T cell number |
increased T cell number |
absent spleen germinal center |
increased splenocyte number |
decreased IgG level |
abnormal CD4-positive, alpha-beta T cell physiology |
lymph node hyperplasia |
lymphoid hyperplasia |
abnormal humoral immune response |
increased interferon-gamma secretion |
decreased susceptibility to autoimmune diabetes |
increased susceptibility to autoimmune diabetes |
increased autoantibody level |
abnormal inflammatory response |
|
Availability | Mouse Genotype | ||||||||||||||||||||||
Cd86tm1Shr/Cd86tm1Shr | |||||||||||||||||||||||
Tg(H2-K-Cd86)7All/0 | ! | ||||||||||||||||||||||
Tg(H2-K-Cd86)27All/0 | |||||||||||||||||||||||
Tg(H2-K-Cd86)31All/0 | |||||||||||||||||||||||
Tg(Igh-6-Cd86)1Akab/0 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 07/05/2024 MGI 6.24 |
|
|