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Symbol Name ID |
Cd80
CD80 antigen MGI:101775 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Autoimmunity |
| Disease(s) Associated with CD80 | |
| type 1 diabetes mellitus |
| Mouse Phenotypes | decreased B cell proliferation |
insulitis |
decreased immature B cell number |
decreased mature B cell number |
decreased B-2 B cell number |
decreased follicular B cell number |
decreased B cell number |
abnormal T cell number |
abnormal B cell activation |
abnormal immunoglobulin level |
decreased IgG1 level |
decreased IgG2b level |
decreased IgG3 level |
decreased IgM level |
decreased immunoglobulin level |
abnormal T cell physiology |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal CD8-positive, alpha-beta T cell physiology |
abnormal T cell activation |
abnormal level of surface class II molecules |
abnormal humoral immune response |
decreased susceptibility to autoimmune diabetes |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Cd80tm1Lbgn/Cd80tm1Lbgn | |||||||||||||||||||||||
| Cd80tm1Shr/Cd80tm1Shr | |||||||||||||||||||||||
| Tg(Igh-6-Cd80)1Gjf/0 | ! | ||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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