Symbol Name ID |
Cav1
caveolin 1, caveolae protein MGI:102709 |
Darker colors indicate more annotations |
Human Phenotypes | Splenomegaly |
Hepatosplenomegaly |
Disease(s) Associated with CAV1 | ||
congenital generalized lipodystrophy type 3 |
Mouse Phenotypes | abnormal osteoclast morphology |
abnormal neutrophil physiology |
impaired neutrophil recruitment |
abnormal macrophage physiology |
increased circulating CXCL10 level |
increased circulating interferon-gamma level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
abnormal cytokine level |
abnormal chemokine secretion |
decreased susceptibility to endotoxin shock |
lung inflammation |
increased susceptibility to bacterial infection |
increased susceptibility to bacterial infection induced morbidity/mortality |
|
Availability | Mouse Genotype | ||||||||||||||
Cav1tm1Mls/Cav1tm1Mls |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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