Symbol Name ID |
Il15
interleukin 15 MGI:103014 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Autoimmunity |
Asthma |
Disease(s) Associated with IL15 | ||
asthma | ||
type 1 diabetes mellitus |
Mouse Phenotypes | immune system phenotype |
absent uterine NK cells |
abnormal thymus cell ratio |
enlarged spleen |
abnormal CD8-positive, alpha-beta T cell differentiation |
decreased dendritic cell number |
decreased NK cell number |
increased NK cell number |
abnormal T cell subpopulation ratio |
decreased CD8-positive, alpha-beta T cell number |
abnormal NK T cell number |
decreased NK T cell number |
decreased CD8-positive, gamma-delta intraepithelial T cell number |
decreased memory T cell number |
increased memory T cell number |
decreased regulatory T cell number |
increased lymphocyte cell number |
abnormal lymphocyte morphology |
abnormal T cell morphology |
increased spleen white pulp amount |
abnormal lymphocyte physiology |
decreased IgG level |
decreased IgM level |
decreased immunoglobulin level |
impaired natural killer cell mediated cytotoxicity |
abnormal CD8-positive, alpha-beta T cell physiology |
increased circulating interleukin-15 level |
abnormal interleukin level |
abnormal immune system morphology |
enlarged lymph nodes |
small lymph nodes |
abnormal immune system physiology |
abnormal dendritic cell physiology |
decreased susceptibility to type IV hypersensitivity reaction |
abnormal cytokine secretion |
decreased interferon-gamma secretion |
abnormal interleukin secretion |
decreased interleukin-12 secretion |
abnormal inflammatory response |
dermatitis |
abnormal susceptibility to infection |
decreased susceptibility to bacterial infection induced morbidity/mortality |
increased susceptibility to Herpesvirales infection induced morbidity/mortality |
increased susceptibility to Poxviridae infection induced morbidity/mortality |
increased susceptibility to parasitic infection |
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Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||
Il15m1Hwata/Il15m1Hwata | ||||||||||||||||||||||||||||||||||||||||||||||
Il15tm1Imx/Il15tm1Imx | ||||||||||||||||||||||||||||||||||||||||||||||
Il15tm1.1Iku/Il15+ | * | |||||||||||||||||||||||||||||||||||||||||||||
Tg(ACTA1-Il15)10941Lsq/0 | ||||||||||||||||||||||||||||||||||||||||||||||
Tg(ACTA1-Il15*)11650Lsq/0 | ||||||||||||||||||||||||||||||||||||||||||||||
Tg(H2-D-Il15)3304Clgr/? |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 07/05/2024 MGI 6.24 |
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